CNS Clinical Research
There is a significant medical need for new psychiatric drug therapies. However, the predictive validity of preclinical methods to detect the potential efficacy of novel compounds is poor. A lack of common endpoints between preclinical and clinical measures have also proved to be major limitations in drug development.
Experimental models, including those that utilize neuroimaging technologies, have provided important insights into our understanding of psychiatric disease. Consequently, these approaches are becoming increasingly valuable for drug discovery and development, and the potential translation of preclinical promise to clinical therapeutic benefit